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产品描述： Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections
靶点： Bacterial;Antibiotic
体内研究： Cefmetazole sodium (Sodium cefmetazole) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora
参考文献：
1. Truesdell SE, et, al. Interaction of cephalosporins with penicillin-binding proteins of methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother. 1989 Apr;23 Suppl D:13-9. 2. Schentag JJ, et, al. Cefmetazole sodium: pharmacology, pharmacokinetics, and clinical trials. Pharmacotherapy. 1991;11(1):2-19. 3. Yaguchi Y, et, al. Influences of long-term antibiotic administration on Peyer's patch lymphocytes and mucosal immunoglobulin A levels in a mouse model. JPEN J Parenter Enteral Nutr. 2006 Sep-Oct;30(5):395-8; discussion 399.
溶解性： DMSO : 250 mg/mL (506.57 mM; Need ultrasonic) H2O : 100 mg/mL (202.63 mM; Need ultrasonic)
保存条件： 2-8℃
配置溶液浓度参考：
1mg 5mg 10mg 1 mM 2.026 ml 10.131 ml 20.263 ml 5 mM 0.405 ml 2.026 ml 4.053 ml 10 mM 0.203 ml 1.013 ml 2.026 ml 50 mM 0.041 ml 0.203 ml 0.405 ml